All episodes

In this episode, we examine how metabolic rewiring and genetic alterations drive cancer and neurological disease. We explore disrupted glycogen metabolism in rare neurodegenerative disorders, altered glucose utilization in leukemia, and the role of lipid metabolism in solid tumors.
The conversation also highlights how key genetic mutations, such as those affecting TP53, reshape cellular pathways and disease progression. By examining these molecular changes across different diseases, we highlight how metabolism and genetics shape disease biology, revealing vulnerabilities that could be exploited for future therapeutic strategies."

This podcast brings together PhD researchers from the University of Bologna to explore how biomaterials and advanced technologies are shaping the future of dental and orthopedic implants.Covering topics from soft tissue regeneration and personalized implants to innovative materials and anti-infective surfaces, the episode highlights research focused on improving implant success and enhancing patient quality of life

In this episode, we explore the fascinating world of biomarkers in cardiovascular and liver diseases.Biomarkers are measurable indicators of a biological state that help detect disease, assess its severity, and predict its progression.By understanding the molecular mechanisms underlying these conditions, we can move closer to more effective and personalized treatments.

In this episode, we dive into the complex journey of cancer treatment, from traditional therapies like chemotherapy to emerging options such as cancer vaccines and personalized approaches like CAR-T cell therapy.We discuss how cancer begins at the genetic level through mutations and how these changes disrupt normal cell functions.Understanding these processes is key to improving early detection and developing more effective, targeted interventions.

In this episode, we reflect on the evolving role of animal modelsin biomedical research, examining ethical concerns, current regulations, andemerging alternatives such as organoids and in silico approaches.

This episode explores the emerging field of sleep medicine through the lens of PhD research.Our guests delve into topics ranging from narcolepsy and neurodegeneration to pediatric sleep health and chronic orofacial pain.We examine the intersection of neuroscience, clinical care, and personal growth, highlighting both the challenges and rewards of pursuing a research career in this vital yet often overlooked area of healthcare.

In this episode, we explore the multifaceted world of epilepsy—its clinical diversity, genetic roots, and therapeutic challenges—throughinnovative research in biomarkers, in vitro models, EEG technologies, andpersonalized drug monitoring.

This episode present a novel MRI classification for lumbar stenosis integrating radiological findings with structured clinical outcomes, mechanoreceptor mapping in the sinus tarsi to optimize flatfoot correction, and biomechanical strategies for talar osteochondral lesion repair via calcaneal osteotomies. We highlight how advanced imaging, molecular insights, and biomechanic concepts converge to drive orthopedic innovation  

This episode explores innovative strategies in joint preservation and regenerative orthopedic surgery, including meniscal allograft transplantation, corrective osteotomies, cartilage repair techniques, and total joint replacement.Focus is placed on biomechanical principles, clinical outcomes, and emerging approaches aimed at restoring joint function, preventing degeneration, and enhancing long-term quality of life.

In this episode, we delve into cutting-edge research on rare neurological and neurodegenerative disorders, exploring advanced molecular diagnostics, cellular and organoid models, and innovative strategies for understanding and treating complex brain and mitochondrial diseases