Beyond the lab: PhDIBINEM - Unibo

This episode will present: the development of an innovative therapeutic platform for CDKL5 Deficiency Disorder as a non invasive, accessible oral treatment using engineered bacteria as a therapeutic vehicle; photobiomodulation as a potential new non invasive therapy for skeletal muscle tissue regeneration; a 3D model differentiated from perinatal stem cells as a potential therapy for type 1 diabetes; and a multidimensional approach to post transplant outcome assessment based on outcome indicators and interdisciplinary interventions.

In this episode, we examine how metabolic rewiring and genetic alterations drive cancer and neurological disease. We explore disrupted glycogen metabolism in rare neurodegenerative disorders, altered glucose utilization in leukemia, and the role of lipid metabolism in solid tumors.
The conversation also highlights how key genetic mutations, such as those affecting TP53, reshape cellular pathways and disease progression. By examining these molecular changes across different diseases, we highlight how metabolism and genetics shape disease biology, revealing vulnerabilities that could be exploited for future therapeutic strategies."

This podcast brings together PhD researchers from the University of Bologna to explore how biomaterials and advanced technologies are shaping the future of dental and orthopedic implants.Covering topics from soft tissue regeneration and personalized implants to innovative materials and anti-infective surfaces, the episode highlights research focused on improving implant success and enhancing patient quality of life

In this episode, we explore the fascinating world of biomarkers in cardiovascular and liver diseases.Biomarkers are measurable indicators of a biological state that help detect disease, assess its severity, and predict its progression.By understanding the molecular mechanisms underlying these conditions, we can move closer to more effective and personalized treatments.